ADA Highlights 2020

Acute decreases in eGFR are relatively uncommon, and are a cause of major concern

Acute decreases in eGFR are relatively common, and when occurring canagliflozin should be discontinued

Acute decreases in eGFR are relatively common, but are usually not a safety concern

An acute decrease in eGFR of no more than50% following initiation of canagliflozin does not appear to be a safety concern

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